Methoxsalen is
used along with controlled ultraviolet light (UVA) to cause a return in skin
color in patients with a certain skin condition (vitiligo). Methoxsalen works by
making the skin more sensitive to UVA light. This combination helps to increase
the number of pigment-producing cells (melanocytes) in the skin.
Methoxsalen is a drug used to treat psoriasis, eczema, vitiligo, and some
cutaneous Lymphomas in conjunction with exposing the skin to sunlight.
Methoxsalen is extracted from Ammi majus, a plant of the family Apiaceae.
Methoxsalen modifies the way skin cells receive the UVA radiation, allegedly
clearing up the disease. The dosage comes in 10 mg tablets, which are taken in
the amount of 30 mg 75 minutes before a PUVA (psoralen + UVA) light treatment.
The substance is also present in other Apiaceae as well as Rutaceae, for example
bergamot oil which is used in many perfumes and aromatherapy oils.
Methoxsalen is a
naturally occurring substance that is reactive to light. It works by enhancing
the body's sensitivity to ultraviolet light A (UVA). Methoxsalen is used in
combination with UVA light therapy to treat severe psoriasis. Methoxsalen is
usually given after other psoriasis medications have been tried without
successful treatment of symptoms.
However,
Patients with high blood pressure or a history of liver problems are at risk for
inflammation and irreparable damage to both liver and skin. The eyes must be
protected from UVA radiation. Side effects include nausea, headaches, dizziness,
and in rare cases insomnia. Methoxsalen has also been classified as an IARC
Group 1 carcinogen (known to cause cancer) but is only cancerous when combined
with Ultra Violet-A radiation.
Readmore:
Methoxsalen online
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