What is n-Butyl isocyanate

Name:n-Butyl isocyanate
CAS NO. 111-36-4
FORMULA C4H9NCO
MOL WT. 99.13
SYNONYMS 1-Isocyanatobutane; Butyl Isocyanate;  Isocyanic acid butyl ester; n-Butylisocyanat (Dutch); n-Butilo isocianato (Spanish);  Isocianato de butilo (Spanish); Isocyanate de butyle (French); 
n-Butyl isocyanate  is an unstable (explosive), poisonous, volatile, clear liquid with the structure of H-O-C≡N (the oxoacid formed from the pseudohalogen cyanide), which is readily converted to cyamelide and fulminic acid. There is another isomeric cyanic acid with the structure of H-N=C=O, called n-Butyl isocyanate . Cyanate group (and isocyanate group) can react with itself. Cyanuric acid (also called pyrolithic acid), white monoclinic crystal with the structure of [HOC(NCOH)2N], is the trimer of cyanic acid.

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What is n-Butyl isocyanate

Name:n-Butyl isocyanate
CAS NO. 111-36-4
FORMULA C4H9NCO
MOL WT. 99.13
SYNONYMS 1-Isocyanatobutane; Butyl Isocyanate;  Isocyanic acid butyl ester; n-Butylisocyanat (Dutch); n-Butilo isocianato (Spanish);  Isocianato de butilo (Spanish); Isocyanate de butyle (French); 
n-Butyl isocyanate  is an unstable (explosive), poisonous, volatile, clear liquid with the structure of H-O-C≡N (the oxoacid formed from the pseudohalogen cyanide), which is readily converted to cyamelide and fulminic acid. There is another isomeric cyanic acid with the structure of H-N=C=O, called n-Butyl isocyanate . Cyanate group (and isocyanate group) can react with itself. Cyanuric acid (also called pyrolithic acid), white monoclinic crystal with the structure of [HOC(NCOH)2N], is the trimer of cyanic acid.

Readmore: n-Butyl isocyanate  online
The article reprinted from:http://www.chemical-chem.com/blog/post8/

The main applications about Ephedrine hydrochloride

Ephedrine hydrochloride  is a medicine which is used in emergency treatment of asthma, asthma, preventing or treating bronchospasm in asthma, bronchitis or chronic obstructive pulmonary disease, treatment of reversible airways obstruction and asthma with seasonal allergic rhinitis. Ephedrine hydrochloride is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history. Respiratory conditions, including asthma, nasal swelling, and nasal congestion. It is also claimed to be a heart and nervous system stimulant. It may have other uses. Check with your pharmacist for more details regarding the particular brand you use.

Ephedrine hydrochloride is an herbal product. It works by stimulating the nervous system, which can increase heart rate and blood pressure. It good for cardiovascular system : so that the skin, mucous membrane and offal vasoconstriction, reducing blood flow; Coronary artery and cerebral vascular dilation, Lee said. After the administration hypertension and pulse pressure intensified. So enhanced cardiac contractility and cardiac output increased. Because high blood pressure reflex excitement to the vagus nerve, the heart rate the same or slightly less. It good for bronchial : relaxation of bronchial smooth muscle, the effect of α fair so bronchial mucosa vasoconstriction, reducing congestion and edema and improve small airway obstruction. But the long-term application of the anti-induced mucosal vascular excessive contraction, capillary pressure, anti-increasing congestion and edema. In addition, the effect of α fair increase bronchial smooth muscle spasm.  It good for central nervous system : exciting cortex and subcortical hub mental excitement, insomnia, anxiety and tremors.

Ephedrine hydrochloride indications :
1. For the prevention of bronchial asthma and mitigation mild asthma attack, the severe acute asthma patient.

2. For subarachnoid anesthesia or epidural anesthesia-induced hypotension low blood pressure and chronic disease.

3. The treatment of the causes nasal congestion, nasal swelling caused.

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Capsiate increased fat burning

Capsiate increases the rate at which the body burns calories, even at rest, by up-regulating mitochondrial function and at the same time acting as a selective sympathomimetic . As would be predicted, this results in increased metabolic rate and increased fat burning both in rats and in humans. Capsiate is a natural product consisting of capsinoids extracted from non-pungent sweet pepper plants.  Capsiate have been shown to increase post-meal energy expenditure, increase lipid oxidation, and reduce food and fat intake.  They have also been shown to increase fat burning in humans through stimulation of the sympathetic nervous system.

The advantages of Capsiate include an increase in your metabolism without increasing blood pressure or heart rate.  Unlike other appetite suppressants, Capsiate  is a natural product that is safe to use long term for weight loss maintenance.  The supplement has no known side effects and does not interact with other prescription medications, making it safe to take even if you have a history of high blood pressure, diabetes or high cholesterol. Capsiate  is offered in easy-to-swallow vegetarian softgels to be taken each morning before breakfast. It is a diet supplement containing dihydrocapsiate, a chemical found in chili peppers that  manufacturers describe as “a great tool for weight management.” Their premise is that capsiate will increase one’s metabolism and burn extra calories much like capsaisin does, capsaisin being another chili pepper chemical that is unfortunately too hot for most tongues.

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The uses and properties of Sodium Borohydride

Name: Sodium BorohydrideCAS NO. 16940-66-2 
EINECS NO. 241-004-4
FORMULA NaBH4
MOL WT. 37.83
SYNONYMS Sodium tetrahydroborate; SBH;
PHYSICAL STATE white crystalline powder particle
MELTING POINT 400 C 
FLASH POINT 250 C
STABILITY Not available. Hygroscopic (dangerous when wet)

Sodium Borohydride is an odorless white to gray-white microcrystalline powder which often forms lumps. It is soluble in water, without decomposition, however it reacts vigorously with acid solutions. Sodium borohydride also known as sodium tetrahydridoborate, is an inorganic compound with the formula NaBH4. This white solid, usually encountered as a powder, is a versatile reducing agent that finds wide application in chemistry, both in the laboratory and on a technical scale. Large amounts are used for bleaching wood pulp. The compound is insoluble in ether, and soluble in glyme solvents, methanol and water, but reacts with the latter two in the absence of base.

Sodium Borohydride is a milder reducing agent, can be used in aqueous solution. It converts selectively aldehydes and ketones the corresponding alcohols in the manufacture of pharmaceuticals and other fine chemicals. It will not react with esters, amides, or carboxylic acids, the more powerful reducing agent lithium aluminum hydride(LAH) is used to reduce these compounds. LAH is the more powerful reducing agent than sodium borohydride due to the weaker Al-H bond compared to the B-H bond. The reactivity of sodium borohydride can be modified by addition of iodine or methanol in BH3-THF to reduce esters into the corresponding alcohols like the reaction of benzyl benzoate to benzyl alcohol. Sodium borohydride is used as a hydrogen source for fuel cell systems and a foaming agent for rubbers. Sodium cyanoborohydride converts certain alcohol groups to methylene groups. Sodium Cyanoborohydride is used as a selective amination reductant. It converts aldehydes (chemoselective), ketones (stereoselective) to the corresponding alcohols in the manufacture of pharmaceuticals and other fine chemicals. It is used in the reductive alkylation of amines, novel metals and oximes.

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The applications and properties of Ubenimex

Name  Ubenimex Synonyms:  Bestatin; [S-(R*,S*)]-N-(3-Amino-2-hydroxy-1-oxo-4-phenylbuty1)-L-leucine 
Molecular Formula  C16H24N2O4
Molecular Weight  308.38
CAS  Number  58970-76-6
EINECS  261-529-2
Melting point  245 ºC

Ubenimex  is also known as bestatin, is a competitive protease inhibitor. It is an inhibitor of aminopeptidase B, leukotriene A4 hydrolase, aminopeptidase N. It is being studied for use in the treatment of acute myelocytic leukemia.

Ubenimex  is an antitumor agent effective against murine syngeneic tumors including mouse colon 26 and C1498 leukemia. It was active against MNNG-induced rat tumor by oral administration. Soluble in acetic acid, DMSO and methanol. Less soluble in water. Insoluble in ethyl acetate, benzene, hexane and chloroform.

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How does Cellactose 80 work?

Cellactose 80 is a spray-dried compound consisting of 75 % α-lactose monohydrate [Ph.Eur./USP-NF/JP] and 25 % cellulose powder dry matter. Cellactose 80, designed especially for direct tableting, combines filling and binding properties of the two excipients which have been synergistically combined to an one-body excipient providing better tableting performance at lower cost.

Cellactose 80 is an inovative filler-binder particularly designed and co-processed for direct compression. Cellactose 80 is a spraydried one-body-compound consisting of 75% alpha-lactose monohydrate and 25% cellulose powder. The advantage of copressing is the synergistic effect of both components, i.e. enhanced compressibility of pure lactose and highly increased flowability of cellulose powder. Spraydrying leads to almost spherical particles of Cellactose 80. It is the content of cellulose that is responsible for its excellent binding capacity. Due to the excellent compressibility of Cellactose 80 tablets with good properties can be obtained at low compression forces. The most obvious advantages of Cellactose 80 are compressibility, flowability, stability, adherence capacity, and pleasant taste. Cellactose 80 is mainly used for high-dosage tablet and for herbal formulations. Cellactose 80 shows superior adherence capacity for small sized actives and therefore provides a very good content uniformity.

Cellactose 80 1 spraydried body 75% of α-lactose monohydrate and 25% cellulose powder compounds. The advantage copressing two components, that is pure lactose enhanced the mobility of the compressibility and high-cellulose powder increased synergies. Spraydrying lead almost Cellactose 80 spherical particles. It is the cellulose content is responsible for its good binding capacity. With the performance Cellactose 80 slices good compression, you can get at low compression force. Cellactose 80 The most obvious advantage is that the compressibility, mobility, stability, and the ability to hold and pleasant taste.

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