The main applications about Ephedrine hydrochloride

Ephedrine hydrochloride  is a medicine which is used in emergency treatment of asthma, asthma, preventing or treating bronchospasm in asthma, bronchitis or chronic obstructive pulmonary disease, treatment of reversible airways obstruction and asthma with seasonal allergic rhinitis. Ephedrine hydrochloride is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history. Respiratory conditions, including asthma, nasal swelling, and nasal congestion. It is also claimed to be a heart and nervous system stimulant. It may have other uses. Check with your pharmacist for more details regarding the particular brand you use.

Ephedrine hydrochloride is an herbal product. It works by stimulating the nervous system, which can increase heart rate and blood pressure. It good for cardiovascular system : so that the skin, mucous membrane and offal vasoconstriction, reducing blood flow; Coronary artery and cerebral vascular dilation, Lee said. After the administration hypertension and pulse pressure intensified. So enhanced cardiac contractility and cardiac output increased. Because high blood pressure reflex excitement to the vagus nerve, the heart rate the same or slightly less. It good for bronchial : relaxation of bronchial smooth muscle, the effect of α fair so bronchial mucosa vasoconstriction, reducing congestion and edema and improve small airway obstruction. But the long-term application of the anti-induced mucosal vascular excessive contraction, capillary pressure, anti-increasing congestion and edema. In addition, the effect of α fair increase bronchial smooth muscle spasm.  It good for central nervous system : exciting cortex and subcortical hub mental excitement, insomnia, anxiety and tremors.

Ephedrine hydrochloride indications :
1. For the prevention of bronchial asthma and mitigation mild asthma attack, the severe acute asthma patient.

2. For subarachnoid anesthesia or epidural anesthesia-induced hypotension low blood pressure and chronic disease.

3. The treatment of the causes nasal congestion, nasal swelling caused.

Readmore:Ephedrine hydrochloride online

Reprint:http://www.advanced-chemicla.net//blog/view.asp?id=6

The uses and properties of Sodium Borohydride

Name: Sodium BorohydrideCAS NO. 16940-66-2 
EINECS NO. 241-004-4
FORMULA NaBH4
MOL WT. 37.83
SYNONYMS Sodium tetrahydroborate; SBH;
PHYSICAL STATE white crystalline powder particle
MELTING POINT 400 C 
FLASH POINT 250 C
STABILITY Not available. Hygroscopic (dangerous when wet)

Sodium Borohydride is an odorless white to gray-white microcrystalline powder which often forms lumps. It is soluble in water, without decomposition, however it reacts vigorously with acid solutions. Sodium borohydride also known as sodium tetrahydridoborate, is an inorganic compound with the formula NaBH4. This white solid, usually encountered as a powder, is a versatile reducing agent that finds wide application in chemistry, both in the laboratory and on a technical scale. Large amounts are used for bleaching wood pulp. The compound is insoluble in ether, and soluble in glyme solvents, methanol and water, but reacts with the latter two in the absence of base.

Sodium Borohydride is a milder reducing agent, can be used in aqueous solution. It converts selectively aldehydes and ketones the corresponding alcohols in the manufacture of pharmaceuticals and other fine chemicals. It will not react with esters, amides, or carboxylic acids, the more powerful reducing agent lithium aluminum hydride(LAH) is used to reduce these compounds. LAH is the more powerful reducing agent than sodium borohydride due to the weaker Al-H bond compared to the B-H bond. The reactivity of sodium borohydride can be modified by addition of iodine or methanol in BH3-THF to reduce esters into the corresponding alcohols like the reaction of benzyl benzoate to benzyl alcohol. Sodium borohydride is used as a hydrogen source for fuel cell systems and a foaming agent for rubbers. Sodium cyanoborohydride converts certain alcohol groups to methylene groups. Sodium Cyanoborohydride is used as a selective amination reductant. It converts aldehydes (chemoselective), ketones (stereoselective) to the corresponding alcohols in the manufacture of pharmaceuticals and other fine chemicals. It is used in the reductive alkylation of amines, novel metals and oximes.

Readmore:Sodium Borohydride online

Reprint:http://www.hydride-china.net/blog/view.asp?id=15

The applications and properties of Ubenimex

Name  Ubenimex Synonyms:  Bestatin; [S-(R*,S*)]-N-(3-Amino-2-hydroxy-1-oxo-4-phenylbuty1)-L-leucine 
Molecular Formula  C16H24N2O4
Molecular Weight  308.38
CAS  Number  58970-76-6
EINECS  261-529-2
Melting point  245 ºC

Ubenimex  is also known as bestatin, is a competitive protease inhibitor. It is an inhibitor of aminopeptidase B, leukotriene A4 hydrolase, aminopeptidase N. It is being studied for use in the treatment of acute myelocytic leukemia.

Ubenimex  is an antitumor agent effective against murine syngeneic tumors including mouse colon 26 and C1498 leukemia. It was active against MNNG-induced rat tumor by oral administration. Soluble in acetic acid, DMSO and methanol. Less soluble in water. Insoluble in ethyl acetate, benzene, hexane and chloroform.

Readmore:Ubenimex  online

Reprint:http://www.poly-peptides.com/blog/view.asp?id=23

The properties and uses of CBZ-Cl

Name: CBZ-Cl

CAS No.: 501-53-1

Molecular formula: C8H7ClO2
Molecular Weight: 170.59
CBZ-Cl  Physical and chemical properties:
Dissolved: soluble in ether and acetone, decomposition in water and ethanol;
Properties: colorless to yellow oily liquid, has a strong irritating odor;
3, boiling point: 103 ° C;
4, the refractive index: 1.5160;
5, the proportion of :1.195-1 .22;
Toxicity LD50 (mg / kg): mice by mouth 3300;

Appearance: colorless to pale yellow oily liquid, irritating and tear.
Purposes: CBZ-Cl  for organic synthesis intermediates, pharmaceutical intermediate synthesis of the amino protective agent can be used Pd / C hydrogenation to take off.

Readmore:CBZ-Cl  online

Reprint:http://www.chemical-chem.com/blog/view.asp?id=11